HOME MAKE A DONATION Tay-Sachs Disease Research Initiatives Fundraising About CTSF

June 2007 October 2007	July 2007 November 2007	August 2007 December 2007	September 2007
February 2008 December 2008	March 2008	June 2008	September 2008
March 2009	June 2009	December 2009
March 2010	June 2010	December 2010
February 2012	July 2012
September 2013
December 2014
February 2015	August 2015	October 2015
July 2016

View the current Research Update in PDF Form

The CTSF began funding a GM2 Inhibitor study being conducted at Boston College in January 2016. The study has two parts - testing the substrate known as 3f alone and in combination with the ketogenic diet. The first part of the study has been complete, testing the 3f alone and the results showed a 13% reduction in GM2 - which is significant!! You can see the progress report by clicking the link above.

The second phase of the study has been started incorporating the ketogenic diet. We will post those results when the work is done. This inhibitor substrate (3f) is the property of the University of Michigan so they control its rights and pace to market. Our goal is only to determine if the drug would be a useful treatment for Tay-Sachs. While the inhibitor is not a cure - it does appear to be a promising tool to slow the pace of the disease as we search for a better option.

This update will be posted on the Cure Tay-Sachs website under Current Research Updates. If you have any questions or comments about this update I can be reached at ken.bihn@curetay-sachs.org or you can call the foundation offices at (216) 812-5855. More updates will be posted as they become available.

Kenneth Bihn - President - Cure Tay-Sachs Foundation